Abstract The microtubules that comprise mitotic spindles in animal cells are nucleated at centrosomes and by spindle assembly factors that are activated in the vicinity of chromatin. Indirect evidence has suggested that microtubules also might be nucleated from pre-existing microtubules throughout the spindle, but this process has not been […]

Cliquez ici pour lire la suite Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2.